Clinical Use Strategies for GLP-1s

PCOS symptoms often intensify after 30 due to compounding insulin resistance, adrenal stress patterns, and brain–ovary signaling changes. As estrogen and progesterone begin subtle shifts in the mid-30s, many women experience more anovulatory cycles, higher cortisol responses, and worsening androgen symptoms.

This episode takes a whole-system view of PCOS across the lifespan and reframes the condition not as a failure—but as a genetically programmed survival adaptation interacting with a modern environment that our biology wasn’t built for.

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