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Episode 26 - Hyperkalemia

The Curious Clinicians

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Is Hypertonic Saline a Better Treatment for Hyperkalemia?

Since at least 1918, hypertonic saline has been shown to be effective at combating all these cardiotoxic effects of hyperkalemia. And what's interesting is so just as with calcium,hypertonic saline can increase the velocity of phase zero depolarization and improves that V max. If you dump a whole ton of sodium into the extracellular space, it's going to increased the velocity of sodium flow across those sodium channels. But one thing to think about it on this topic is sodium bicarbonate,. So if you decide to give that for hyperKalemia, it may in fact be the sodium in the sodium bic carbonate that's more important than

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