
Food & Metabolomics: How Your Diet—Starting in Childhood—Shapes Your Brain | Dr. Alexis Wood
The Dr. Gabrielle Lyon Show
Intro
This chapter explores the vital connection between childhood nutrition and cognitive health, detailing how dietary choices influence brain development. It also highlights the need for more interdisciplinary research to address gaps in understanding the long-term effects of nutrition on cognitive and social outcomes.
In this episode, Dr. Alexis Wood, a leading researcher at Baylor College of Medicine, joins me to unpack insights into childhood nutrition, genetics, and cognitive health. Dr. Wood's work bridges genetics, dietary practices, and brain development, highlighting how early-life nutrition can shape lifelong outcomes. We explore cutting-edge research, practical strategies for parents, and the surprising factors influencing children's cognitive and metabolic health.
We cover:
- Why childhood nutrition and genetics have been historically overlooked—and what it means for your family.
- ADHD and diet: Separating fact from fiction.
- Debunking popular diet myths: What the research actually says about red meat and processed foods.
- Cognitive self-regulation: The hidden link between diet, obesity, and ADHD.
- Precision nutrition & metabolomics: The future is more than one-size-fits-all advice.
Whether you're a parent, educator, or health professional, this conversation offers guidance on navigating the complex relationship between nutrition, genetics, and childhood development.
Who is Dr. Alexis Wood?
Dr. Alexis Wood, Ph.D., F.A.H.A., is an Associate Professor of Pediatrics–Nutrition at Baylor College of Medicine’s USDA/ARS Children’s Nutrition Research Center. Her research integrates genetics, child development, and nutrition, focusing on how genetic factors influence responses to diet and behavior.
This episode is brought to you by:
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Find Dr. Alexis Wood at:
- Linked In - https://www.linkedin.com/in/lekkiwood/
- Baylor College of Medicine - https://www.bcm.edu/people-search/alexis-wood-33281
- USDA/ARS Children's Nutrition Research Center - https://www.bcm.edu/research/research-centers/usda-ars-childrens-nutrition-research-center
- Alexis Wood Lab - https://www.bcm.edu/research/faculty-labs/alexis-lekki-wood-lab
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Timestamps:
00:00 - Introduction and overview
01:25 - Current landscape of childhood nutrition and genetics
04:00 - Challenges and opportunities in studying child nutrition
07:39 - ADHD, genetics, and dietary myths
12:23 - Clinical evidence on diet and ADHD
14:18 - The Mediterranean diet and childhood nutrition
17:48 - Debunking myths around red meat consumption
22:55 - Metabolomics: Precision nutrition’s new frontier
28:39 - The genetics of cognitive self-regulation and obesity
34:50 - Nutrition’s role in cognitive health across the lifespan
39:57 - What are metabolites and why do they matter?
44:29 - Interpersonal variability in nutrition responses
48:52 - The milestone "MILES" metabolomics study
52:21 - Processed foods: Balancing health and reality
58:19 - Early life behaviors and aging
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