3min chapter

Behind The Knife: The Surgery Podcast cover image

Doctor Cure Thyself: An Interview With Dr. David Fajgenbaum

Behind The Knife: The Surgery Podcast

CHAPTER

How to Repurpose Drugs for Other Indications

Between 20 and 50 different diseases are considered for every drug that's developed. Only five to 10 are studied in clinical trials and only one to three get approved or the drug is only approved for one to three diseases. So there's this huge funnel of like dozens of diseases for every drugs that are promising but never pursued. And so we're coming at it from two angles. One is leveraging a knowledge graph just down the road from you at UNC, called Rensi. We're generating a score for every drug disease combo.

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