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TWiV 875: Animal house

This Week in Virology

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Could You Evolve Asto Binding?

The idea is that you had ato binding in the ancestor to all these sarbaco viruses. The ancestral vire r b d seems to have it, but we don't know if this actually exists. They say they can make single meno acid changes that will allow ace two binding from a r b d that does not bind a two to begin with. This suggests that human ace two binding is evolutionarily accessible in this lineage.

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