Is Torsimide Better Than Pheurosemide for Heart Failure?

Rahul: I'm going to be talking about the Transform HF Study, and this was the study by men's and colleagues. The research question that these authors were asking was among patients hospitalized with acute heart failure, does torsimide reduce all cause mortality compared with pheurosemide by at least 20% within 12 months? Rahul: Torsimide is thought to block the aldosterone receptor leading to rast inhibition, reduction in myocardial fibrosis. He says it also has better oral bioavailability and a longer half-life than pheuroSemide.