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Underuse of Thiamine in Patients With Alcohol Use Disorder in the Intensive Care Unit

Annals On Call Podcast

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What Do You Think About Thiamine Dosage?

I read we tend to give fairly aggressive thiamine at our hospital but I can't find any good data in the literature to say what the right dose is. In World War II when there was in the Japanese prison camps and people were deprived of thiamine then developed some of these symptoms all they could get was a few milligrams to the soldiers, that even seemed to help them. So you know it's really unclear. But now we kind of know that the half-life is actually quite short so it's probably worth giving thiamine two or three times a day. And finally do you think it matters how much thiamine we give?

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