Exploring Disease, Medicine, and Cellular Dysfunction in Cancer

Welcome to The Orthogonal Bet, an ongoing mini-series that explores the unconventional ideas and delightful patterns that shape our world.

Hosted by Samuel Arbesman, Complexity Scientist, Author, and Scientist in Residence at Lux Capital.

In this episode, Samuel speaks with Philip Ball, a science writer, and formerly a longtime editor at the science journal Nature. Philip is the author of the fantastic new book “How Life Works: A User’s Guide to the New Biology.”

Samuel wanted to talk to Philip because he loved this book. It’s fascinating and deeply provocative, even for someone with a PhD in computational biology—though Samuel’s might be a bit worn and out of date—and yet he still learned so much. The book examines how new advances in our understanding of biology have led scientists to understand that life is far less deterministic than we might imagine. For example, cells are not really machines, as some might have thought, but complex and messy yet robust systems. And while DNA and genes are important, there is so much more going on, from the processes that give rise to the shape of our limbs and our bodies, to how all of this can have implications for rethinking medicine and disease.

Produced by ⁠⁠⁠⁠⁠⁠⁠⁠⁠Christopher Gates⁠⁠⁠⁠⁠⁠⁠⁠⁠

Music by ⁠⁠⁠⁠⁠⁠⁠⁠⁠George Ko⁠⁠⁠⁠⁠⁠⁠⁠⁠ & Suno