The Role of Insulin in Diabetes

One in five of our DKA patients is actually going to be a type 2 diabetic, so it's important that we understand what's going on. In long standing type 2 diabetics, there may be a complete lack of beta cell activity resulting in a lack of insulin secretion. But also some studies suggest that with a constant hyperglycemia resulting from poor control, along with the increased presence of counterregulatory hormones this can cause severe relative insulin deficiency which then can result in the DKA. Now coming back to the DKA, so you might be wondering why it actually occurs and what I mean by that is what actually precipitates it. So for example, if dosages of