What's the Biggest Paradime Shif in Economics?

In 19 76, you published a paper with ogneans. We looked at two paradimes in theories of money supply. You began rather philosophically by discussing thomas coone's structure of scientific revolutions. And i wanted to ask you, what's the biggest paradime shift you've seen in economics during your lifetime? It's a good question, because right now, one of the things that strikes me is how so many of the relationships that we sort of took for granted don't apply, don't apply to the same extent.