Seizure Prophylaxis in Traumatic Brain Injury

The chapter analyzes the effectiveness of anti-seizure medications in preventing seizures in adults with traumatic brain injury, reviewing studies on different medications and their impact on mortality and cognitive outcomes. It explores the challenges in making strong recommendations due to limitations in the literature, underdosing of medications, and lack of standardized monitoring. Discussions also include the comparison between phenytoin and levatoracetam, the optimal duration of medication, and personalized approaches to seizure prophylaxis based on individual patient needs.