This chapter narrates the transformative journey of a patient exploring MDMA-assisted therapy for PTSD following multiple suicide attempts. It highlights the importance of the Multidisciplinary Association for Psychedelic Studies and provides insights into the clinical trial process, including the role of therapists and the impact of both psychedelic and traditional therapeutic methods. The individual’s experience emphasizes profound personal changes and the ongoing challenges of coping with PTSD in the context of relationships and emotional connection.