Understanding Non-Alcoholic Fatty Liver Disease and its Risk Factors

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This chapter provides a comprehensive resource on non-alcoholic fatty liver disease (NAFLD), exploring its definition, impact on metabolic health, and the role of lifestyle factors. It discusses the prevalence and risk factors of NAFLD, including sex and ethnicity variations, as well as the influence of modifiable factors such as diet and physical inactivity. The chapter also highlights the adverse metabolic consequences of fatty liver and the impact of sex differences on adipose tissue.

Episode #281. With nearly a quarter of the world's population estimated to be affected by non-alcoholic fatty liver disease (NAFLD), understanding its intricacies is crucial. Join me as Dr Alan Flanagan helps unravel the complexities of NAFLD, breaks down its wider health ramifications, and offers insights on managing and living with the condition.

We discuss:

Introduction to Fatty Liver Disease (00:00)
Understanding Non-Alcoholic Fatty Liver Disease and Its Development (02:27)
Risk Factors: Gender Differences in Fatty Liver Disease Development (09:33)
The Science of Hepatic Fat Oxidation (14:45)
Consequences and Effects of Fatty Liver Disease (20:25)
Identifying Symptoms of Non-Alcoholic Fatty Liver Disease (25:54)
Risk Assessment: Non-Alcoholic Fatty Liver Disease in Premenopausal Women (29:33)
Energy Toxicity and Misconceptions about BMI (34:50)
Linking Non-Alcoholic Fatty Liver Disease with Type 2 Diabetes (48:34)
Liver Changes During Non-Alcoholic Fatty Liver Disease Progression (1:02:16)
Strategies for Reducing Fat Accumulation in the Liver (1:05:28)
The Role of Time-Restricted Eating in Managing Fatty Liver Disease (1:11:41)
The Impact of Sugars on Fatty Liver Disease (1:20:16)
Understanding the Relationship Between Dietary Fats and Fatty Liver Disease (1:41:16)
High Saturated Fat Diets and Their Effect on Fatty Liver Disease (1:57:19)
Importance of Caloric Source Variation in Dietary Fats (1:59:23)
Beneficial Dietary Patterns for Liver Health (2:04:07)
Analysing Dairy Types and Their Effects on Liver Fat (2:08:29)
Meal Frequency and Its Relation to Liver Fat Accumulation (2:12:40)
Recommended Lifestyle Changes for Preventing Non-Alcoholic Fatty Liver Disease (2:17:59)
Conclusion: Key Takeaways on Fatty Liver Disease Management (2:20:07)

Connect with Alan Flanagan on Instagram, and learn more about his company, Alinea Nutrition, here. Make sure to listen to his five previous appearances on The Proof here.

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Enjoy, friends.

Simon

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Simon Hill, MSc, BSc (Hons)

Creator of theproof.com and host of The Proof with Simon Hill

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