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Aug 11, 2023 This Week in Cardiology Podcast

This Week in Cardiology

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DIG Jackson and Heart Failure Hospitalizations

DIG Jackson has been found to associate with increase in mortality in observational studies, but these are mostly confounded by indication. In the DIG trial, a secondary endpoint was heart failure hospitalizations, and DIG Jackson reduced them by a statistically significant 28%, as much as some of our favorite drugs now think SGLT2 inhibitors. Patients on DIG Jackson before the trial had a 22% higher death rate and a 47% higher heart failure hospitalization rate than those who were not taking it.

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