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Metabolic health truths | Christos Mantzoros MD, DSc, PhD

The Proof with Simon Hill

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Physiological Responses and Weight Loss Strategies

The chapter explores the physiological responses in anorexia nervosa and obesity, such as hormonal changes, effects on inflammation, and the body's resistance to weight loss. It discusses challenges in addressing extreme exercise behavior, sustained weight loss interventions, bariatric surgery's impact on hormone levels, the development of medications for weight loss, and the role of appetite in maintaining lower body weight. Additionally, it touches on the potential positive unintended consequences of weight loss medications on behaviors like alcohol or gambling issues through changes in brain activity.

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