This chapter examines the implications of U.S. sanctions on Venezuela's economy and political landscape under Nicolas Maduro, revealing the unintended consequences of excessive measures. It explores the internal debates within the U.S. government regarding the effectiveness of these sanctions, particularly during the transition from the Trump to Biden administrations. The narrative highlights the intricate relationship between domestic policies, international pressures, and the potential implications for U.S. foreign policy in light of the upcoming 2024 election.