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090CE: RHD Genotyping; We Can do Better! with Sue Johnson

Blood Bank Guy Essentials Podcast

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The Importance of Amino Acid Changes in Red Cell Membrane

80 to 90% of the weak D types that we see are weak D type one, two or three. Their mutations are the base pair changes, which result in an amino acid change. And so you can imagine then is that the amino acids that are exposed that are on the outside of the red cell membrane are all the same. So it does impact expression, but everything on the outside is the same, right? Exactly.

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