
TWiN 26: Immunological memory in the brain
This Week in Neuroscience
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Is It Possible to Zap the End Grass?
Vincent Rackett: These papers are really exciting. But in some ways that this actually makes me more hesitant to believe that this is translatable, because how could you only stimulate the end gram right now? It's easy to slam an electrode in the subthalamic nucleus and have DBS; it's much harder to genetically capture an end gram. That's like leading to a phenotype in a human. Yeah, which might also drift. Exactly. With every single flare up. So I think that it was helpful in understanding the mechanism of memory, but less so in terms of how we can manipulate it ourselves.
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