The EBM Lessons Learned From the Negative Trials

Both trials are equally high quality equally important your clinical practice should be equally shaped by both but clinicians are way more likely to hear about Cape Cod. EBM lesson number two papers are never just positive or negative we shouldn't interpret them based on their p-value so it's quite possible that these two trials are saying the exact same thing. The six percent absolute benefit in Cape Cod just seems too big and trials stopped early do tend to overestimate results.