
2.11 Schizophrenia
Psychiatry Boot Camp
Understanding the Impact of Genetic and Environmental Factors on Schizophrenia
The chapter explores the intricate relationship between genetics and environmental influences in the development of schizophrenia, highlighting factors like cannabis use, trauma, and genetic studies. It discusses the complex interplay of dopamine and glutamate in the disorder, exploring models like the dopamine-ketamine parallel and challenges in developing glutamate-targeting medications. Additionally, it touches on the historical perspectives of schizophrenia research, replicated neuroimaging findings, and debates around lateral ventricle enlargement and dopamine's role in the disorder.
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