Talking Biotech with Dr. Kevin Folta cover image

Dr. Dietrich Stephan: New Drugs that Repair Broken Genes

Talking Biotech with Dr. Kevin Folta

00:00

Huntington's Disease

Shuntington's disease is among the most horrific diseases that any of us will hopefully never encounter. One copy of a gen called huntington has a tri nucletie repet expansion in xon. And when that happens, the resultant protein has with polyglutomine run in it. So there are more of these glotomine molecules that cause the protein to become very sticky and aggregate within neurons. We believe that's the dominant mechanism behind the disease. Those intra neuronal aggregates actually kill the neurons.

Transcript
Play full episode

The AI-powered Podcast Player

Save insights by tapping your headphones, chat with episodes, discover the best highlights - and more!
App store bannerPlay store banner
Get the app