TWiV 1189: Viruses making waves
This Week in Virology
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Comparing Immune Responses to Vaccines
This chapter explores the immune responses elicited by yellow fever and Japanese encephalitis vaccines in dengue-seronegative adults, highlighting the study design that minimized interference from dengue infections. The findings indicate that the yellow fever vaccine generated a stronger immune response, particularly in T cell activation and cytokine release. The discussion also raises intriguing questions about vaccine efficacy in relation to neutralizing antibodies and viral RNA detection, suggesting potential future applications in vaccine strategies.
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