What's the Difference Between a Mushroom and Ore Synthetic Sil Silmon?

In a couple of thousand cases i have, we have onty one person with synthetic solsibon. Three to five grams of mushroom will give youa fairly expansive trip. People have taken much more than that, and at some point they they stop bringing back useful information. In my world, that's what too much of a dose is. Each mushroom has its own level, its its own amount of silicibeand even if you have mushrooms from the same little patch the same species, ill be different. So it's much harder when you get into natural substances.