Lisa: When you're thirsty and you drink a glass of water, you drink until your thirst is quenched. The thing is that the water takes about 20 minutes to make it into your bloodstream to get to your brain. So based on drinking water, your brain is predicting that your thirst will be quenched, but actually it takes about20 minutes for that change to happen. Same thing with hunger. We talk about hunger as being this physical thing, but hunger pain also experiences,. There are physical components to those experiences like how much glucose do you have in your bloodstream, or in the case of pain, how much what's called no-susception that is signals about tissue