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Audio long read: Conquering Alzheimer’s — a look at the therapies of the future

Nature Podcast

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The Effects of Beta Secretes on Alzheimer's Disease

Clinical trials of these drugs all flocked and interested in them dried up until they got a second chance. None of the drugs had shown benefit, and worse, many had toxic side effects including worsened cognition. The goal was to help the field understand more about the disease-related biologies targeted by these investigational drugs. One such modulator, a compound developed in an academic collaboration, will be tested in an early clinical trial this year.

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