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#332 #1 Aging Pathway No One Talks About (Not Protein) - Joel Greene

Siim Land Podcast

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Is There a Solution to Insulin Resistance?

The insulin receptor has lost its ability to respond to insulin and move glucose into the cell. So now what happens is the body's making more insulin to get the same result. The IGF-1 receptor is firing, firing more, but we're not transporting glucose. But what we are doing is activating all these pathways. We're activating the map K pathway. And so that whole thing starts the clock on lifespan, you know, and that's directly tied to insulin.

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