Evolution and Challenges in the Treatment of Difficult to Treat Rheumatoid Arthritis and Related Conditions

The chapter covers the evolution of studying difficult to treat spondyloarthritis and psoriatic arthritis, emphasizing the importance of differentiating between inflammatory and non-inflammatory causes using imaging techniques. It discusses the significance of recognizing and addressing anxiety and depression symptoms in patients with RA for effective treatment outcomes, as well as the impact of depression on mortality rates. Additionally, the chapter reviews a study on continuing biologic therapies during grade two infections and explores the complexities of using AI in analyzing treatment efficacy in rheumatology.