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Chapter Nine: Regulation of Plasma Osmolality

Channel Your Enthusiasm

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CFTR Chloro Channel Chloride in Cystic Fibrosis

The average sodium content in human sweat ranges from 10 to 90 millimoles per liter. High sweat chloride can be helpful to diagnosis of fibrosis, but because there are some healthy individuals who do have a sweat chloride more than 60, these are sometimes termed 'salty sweaters' The study looked at the sweat electrolyte differences in patients with cystic fibrosis and healthy controls. It showed that the sweat chloride in controls was at an average of 23 millimoles every liter compared to 93 millimoles for those with cystic Fibrosis.

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