The Importance of Pregnancy in ED Workups

The role of D dimer pregnancy has been controversial. We know that D dimer increases throughout pregnancy, such that by the third semester, about 95% of patients will have a positive D dimer. But recently there's been two studies that have potential to change what we think about D dimer in pregnancy. The first one is by Vergini et al., 2018. Using this study, the incidence of PE was 7%, and there were zero misseds at three months using this 3-month follow up algorithm. In the New England Medicine trial with Artemis, essentially all the patients in the third trimester had apositive D dimer and required imaging. This study showed us that D