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#60 – Going MAD for Non-COVID ID Literature: A Year in Review LIVE from MAD-ID
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Bayesian Dosing for COVID
Bayesian dosing is preferred but you can also use first order PK equations to get to your AUC. We actually make a difference in real life to give the beta lactam prior to vencomycin so this was a retrospective observational study by pernida tama and colleagues out of john Hopkins. Graham negative blood treatment sections are associated with high and early mortality, and your beta lactam antibiotics can go in quick. Even if you're using a continuous infusion or an extended infusion you're still giving that initial dose as a 30 minute bolus or maybe even less if your drugs are on shortage and you've switched to IV push.
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