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iwNHL Session IV: T-cell therapies for NHL: CAR-T therapies & third-party EBV T-cells

VJHemOnc Podcast

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Advancements in CAR T-cell Therapies for NHL: Targeting CD5 and CD7 Antigens

This chapter discusses the potential of targeting antigens beyond CD19, such as CD5 and CD7, in T-cell lymphoma and acute lymphoblastic leukemia (ALL). It highlights a new approach that generates CD7 CAR T-cells without manipulation using tyrosine kinase inhibitors and mentions a phase one trial with encouraging responses in patients with T-cell lymphoma.

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