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The Sleep Series: Z Drugs (Zolpidem, Zaleplon, EsZopiclone)

PsychRounds: The Psychiatry Podcast

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Intro

This chapter explores the pharmacology of Z-drugs like Zolpidem, Zaleplon, and Eszopiclone, which are widely used for insomnia. It examines their development history, structural differences from benzodiazepines, and their specific mechanisms of action at GABA receptors, along with associated risks.

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