Sin Is a Great Guilt

In Romans 1 verse 18 Paul said, they are suppressing the truth in unrighteousness. In verse 28 they disapproved of having God in their knowledge. So the picture you get is that sin is a failure to embrace the glory of God and God Himself as our highest treasure. It's not surprising that the design of God for a beautiful holistic world would be destroyed in your life. There is dysfunction and chaos and misery all over the world because the whole world is in rebellion against valuing the Glory of God above all things.