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#31 - Navdeep Chandel, Ph.D.: metabolism, mitochondria, and metformin in health and disease

The Peter Attia Drive

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Can a Mitochondrial Dione Modify Gene Expression?

i like to think about h two, o two and t c a cycle metabolites that get released. Theyre very in constant flux between the cydoplasm and the t ca cycle. And they can control gen expression through crometon, through histone modifications. Is that happening often in the mitachondrial dione as well, or are they pretty much just on their ownthe have. So what transcription factors tell those geans when to turn on again? It's all nuclear and coted,. There has to be a reason for this that hasn't ye? Why? You know, mean, i know you're fascinated by mite. Condral d an a and

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