
JAMA Oncology : Lynch Syndrome and Somatic Mismatch Repair Variants in Pancreas Cancer
JAMA Network
00:00
Intro
This chapter examines a study on Lynch Syndrome and somatic mismatch repair variants in pancreatic cancer, highlighting key clinical genomic features and treatment outcomes. It emphasizes the significance of MSI high status as a biomarker for predicting responses to immune checkpoint blockade therapy and discusses the complexities of mismatch repair deficiency.
Transcript
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