Exploring Bat Antibody Stability

This chapter investigates the thermodynamic stability and properties of bat antibodies compared to human antibodies, using techniques like thermal shift assays and hydrophobic interaction chromatography. The discussion highlights unique responses of bat antibodies to ionic strength, polyreactivity, and the implications for immune responses and autoimmunity. Additionally, it delves into experimental methodologies for studying cell death processes and antibody interactions with apoptotic cells, emphasizing future research directions in understanding bat antibodies.