Is Prophylactic Antigen Matching an Effective Strategy?

The argument that so many of these patients they have antibodies at the time of presentation has been used to say that we need to consider matching these patients like we do patients with sickle cell is that argument something that resonates with you Megan? I think it's one of the justifications for why prophylactic matching is something that laboratories might want to do. There are other more laboratory based reasons that sort of harking back to what Lissa was talking about before by doing PAM that maybe you don't have to do repeated adsorptions which can be difficult. It ends up being a judgment call but I think our paper shows pretty clearly that there's a lot going on with