Many psychodalics operate through the tonean system. If i've a seratone in and balance, am i at some kind of special risk, or do we not even know? People n an s s r i will not be admitted to these trials. And the reason is not that there's a counter indication that it would make you sick or do something bad to you, but it won't work. The psychadelic often won't work if you're on an s sr i. So people who want to take them would need to taper off them. But that carries its own risks. Of course, of suicide.

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