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Critical care of neuromuscular disorders

Critical Matters

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Differential Diagnosis of Acute Neuromuscular Weakness

This chapter explores the various causes of acute neuromuscular weakness in patients, ranging from inflammatory to metabolic conditions, emphasizing the need for a comprehensive evaluation in the ICU. It delves into Guillain-Barre syndrome, discussing its epidemiology, pathophysiology, triggers, and different variants like AIDP and Miller Fisher syndrome. The chapter also highlights the diagnostic approach, including clinical assessments, serologic testing, imaging studies, CSF examination, and EMG nerve conduction studies to differentiate and manage neuromuscular disorders effectively.

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