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Ep. 49: “Viruses and Aging” Featuring Dr. Clovis Palmer

The Immunology Podcast

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HIV and Cancer - What's the Parallel Between Glucose Metabolism and Cancer?

Cancer cells require more glucose, more nutrients in order to proliferate. And so therefore, when we look at both cancer and immune cells, we found that there are increased level of aerobic glycolysis. So what's interesting with that similarity is that we have actually been trying to investigate whether or not we could use drugs that have been used for cancer research to help tame the immune responses against infections such as HIV. Do we understand by which mechanism the viral infection is driving this metabolic rewiring of the cells? Yes, very good question.

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