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SGEM#469: You Take My Breath Away – D-dimer for Ruling out PE in High-Risk Patients

The Skeptics Guide to Emergency Medicine

CHAPTER

Unraveling D-Dimer Bias in PE Studies

This chapter examines selection and information bias in studies of D-dimer tests for ruling out pulmonary embolism in high-risk patients, addressing the generalizability of findings and implications of missing data. It emphasizes the need for larger, higher-quality studies to improve clinical decision-making and invites listener engagement through a Keener Contest on related PE topics.

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