Understanding the Sensitivity of the Holy Spirit and Quenching Him

It's a weighty thought to realize that we can disappoint and sadden the Holy Spirit. If we want to fully embrace the presence of the Holy Spirit in our lives, we must first understand that the Holy Spirit can be quenched. But how does it happen? When does it happen? And what can we do to attune to the sensitive nature of the Holy Spirit to ensure we allow Him to do what He wants, in and through our lives?