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Challenges with the Amyloid Hypothesis in Alzheimer's Disease
The chapter explores the repercussions faced by researchers for fabricating data related to the amyloid hypothesis in Alzheimer's disease, shedding light on the emphasis on amyloid rather than addressing root causes like glucose hypometabolism. It discusses the approval and potential risks of a drug for neurodegenerative diseases, the benefits of a ketogenic diet for Alzheimer's patients, and the problematic persistence of prescribing medication based on flawed studies. The chapter also touches on the sunk cost fallacy in academia and pharma, as well as personal experiences illustrating the ineffectiveness of drugs targeting amyloid burden in the brain.