Two Scientists Walk Into a Bar cover image

S4E06: It's Personal: Inclusive Research and Precision Medicine

Two Scientists Walk Into a Bar

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Polygenic Risk Score

The polygenic risk score is another way of determining what's your statistical chance of having any particular disease. For example think about something like having a heart attack. What we're doing is looking at well you have variants X in this gene maybe to do with lipidsYou have another variant in a gene to do with inflammation and we use statistical analysis of big data sets so you get what looks like a fingerprint. It does tell you and your medical professionals that you're perhaps at a higher risk than somebody else. And you wouldn't know that unless you looked at your genes.

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