16min chapter

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E242- (CME) Past, Present, and Future: Muscarinic-Targeting Treatments for Schizophrenia

NEI Podcast

CHAPTER

Targeting Muscarinic Receptors in Schizophrenia Treatment

This chapter explores the potential of muscarinic-targeting treatments, particularly the effects of M1 and M4 agonism on cognitive impairment in dementia and schizophrenia. It examines the balance between treatment effectiveness and the management of side effects, along with the historical context of antipsychotic development. The discussion also highlights the intricate relationship between acetylcholine, dopamine, and the underlying mechanisms that could offer new pathways for successful schizophrenia management.

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