The Single Arm Studies and What are the Alternatives?
The Effective Statistician - in association with PSI
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The Importance of Pros and Cons of Single Arm Trials
Statistics is the science of trying to help people avoid seeing things that are not there. We have to give them a possibility to understand no matter how much they want something to work, there is an alternative explanation. I think trials have to be the letter, not the first. They need to contribute also to the scientific knowledge. And avoiding all the problematic questions by doing a minimalistic design is when the industry refuses to contribute to the building of scientific knowledge.
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