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Insulin Resistance and Muscle Retention
Insulin increases what they call micro-perfusion. It increases the circulation of blood to the muscle fibers. And it does that by stimulating nitric oxide, which is produced in the endothelium. If you don't have enough micro- perfusion into the muscles, the amino acids, now you have anabolic resistance. That's gonna cause muscle loss. You're not getting... If the amino acids can't get into the muscle, there's no anabolic effect. So that's how insulin... Then that's an endlessly way you've got less muscle, and you're burning less calories and your weight's gonna continue to go up.