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TWiV 584: Year of the coronavirus

This Week in Virology

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The Virus Is Attenuated in Cell Culture

Virus is attenuated in cell culture. It may replicate to lower levels in vivo even, but maybe there's some advantage to replicating to lower levels. Maye tes get to more cells that way. That's the key. And they say that their mouse models don't actually reproduce ours, although ralph apparently does. But i think it's quite interesting that this reduces replication. We don't know what it doesnint people whalt.

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