CBD and THC: A Possible Interaction

CBD is a functional antagonist at very low potency of CB one. So presumably there's some interaction between THC and CBD. And I think that's about where it ends when you look at a lot of the compounds in cannabis. These are phenolic natural products. We know that polyphenols from things like grapefruit have massive pharmacodynamic implications, so they can affect how your body responds to other classes of drugs.