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#391 Hypercoagulable Work-Up with Dr. Jean Connors

The Curbsiders Internal Medicine Podcast

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The Problems With Anti-Phospholipid Assays

Anti-phospholipid antibodies were identified first in patients who have lupus. The PTTLA is probably the most commonly used machine that it's used on the stago machine and reagents are pretty prevalent. In vitro, they activate thrombosis, I'm sorry, in vivo. But in the test tube, they slow it down. So what you do for these clot-based assays? There's the dilute rustle viper venom test. There's the kaolin activation assay. And this is either smushed up platelets or platelet neutralization procedure,. You take a lot of excess phospholipid plasma and you add all their anti

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